If I still want to apply changes immediately, I can use the rpm-ostree apply-live command which will apply changes without restarting the system (but some modifications may require a reboot to be fully effective).
The US Environmental Protection Agency’s Response Management Program (RMP) requires more than 12,500 high-risk facilities to develop protocols to prevent catastrophes, or limit fallout, and was largely designed to protect workers, first responders, and fence-line communities.
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